The primary outcome measure was in-hospital all-cause mortality secondary outcome measures were LOS and the number of comorbidities.Ī total of 39,323 inpatients were included in the final analysis. The MELD score on hospital admission was calculated retrospectively. From January 2012 through December 2013, all consecutive inpatients aged 18 years were eligible for the study patients with missing MELD parameters on hospital admission and/or treatments influencing the international normalized ratio, that is, novel oral anticoagulants and vitamin K antagonists, were excluded. We performed a retrospective observational study at a tertiary referral center. We therefore aimed to investigate a potential association of the MELD score with mortality, length of hospital stay (LOS), and disease burden in a general patient population. It shows that according to our study the MELD score has performed better in predicting the post-operative outcome of patients with liver diseases than CTP score.Ĭonclusions: Although CTP and MELD both are widely used to predict the post-operative mortality but in our study MELD score has predicted the outcome more effectively than CTP scoring system.The laboratory-based model for end-stage liver disease (MELD) score reflects the function of the kidney, liver, and extrinsic coagulation pathway and might be used as a general prognostic tool for the assessment of patients. The mean survival time of 56, 54.85, 42.40 for CTP grades of A, B, and C respectively has a P value of 0.582. Significant results were followed-up by pair-wise log rank test, at Bonferroni adjusted α level of p 30 has a P value of <0.001. Pooled log rank test was conducted to determine if there were differences in the survival distributions for the different categories in each group. Kaplan Meyer Survival Analysis was conducted to compare post-op survival time among patients divided on the basis of MELD score and CTP Grade. Statistical analysis used: All the continuous variables were reported as mean ± standard deviation. Scores of both CTP and MELD models were calculated preoperatively and post-operative outcome was compared with them to find out which model was a better predictor of mortality. All the investigations were done by the same institution. All the surgeries were done by the same team of consultant surgeons. Methods and Material: This is an Observational study that was carried out at General Surgery Department of Nishtar Medical University and Hospital from October 2019 to March 2020. Childs-Turcotte-Pugh (CTP) and Model of End-Stage Liver Disease (MELD) scoring systems are globally used to predict post-operative mortality in end stage liver disease patients.Īims: To compare the results of CTP and MELD scoring systems for predicting outcome in patients of chronic liver disease and to conclude which model is better for risk stratification, so as to enable us in better management of these patients. Various prediction models are in use to serve this purpose. The prediction of postoperative outcome is very crucial in the management of these patients. Childs-Turcotte-Pugh (CTP), End Stage Liver Disease, Model of End-Stage Liver Disease (MELD), Post-operative Mortality AbstractĬontext: Patients with liver disease are always at high risk of post-operative complications.
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